Posted inSci/Tech

WHO discontinues hydroxychloroquine and lopinavir/ritonavir trials for COVID-19

July 4, 2020 – WHO today accepted the recommendation from the Solidarity Trial’s International Steering Committee to discontinue the trial’s hydroxychloroquine and lopinavir/ritonavir arms. The Solidarity Trial was established by WHO to find an effective COVID-19 treatment for hospitalized patients. The International Steering Committee formulated the recommendation in light of the evidence for hydroxychloroquine vs […]

Posted inUS

Potential harms of chloroquine, hydroxychloroquine and azithromycin for treating COVID-19

April 9, 2020 – Chloroquine, hydroxychloroquine and azithromycin are being used to treat and prevent COVID-19 despite weak evidence for effectiveness, and physicians and patients should be aware of the drugs’ potentially serious adverse events, states a review in CMAJ (Canadian Medical Association Journal). “Physicians and patients should be aware of several rare but potentially life-threatening adverse […]

Posted inWorld

WHO expert panel strongly advises against use of hydroxychloroquine to prevent covid-19

March 2, 2021 – The anti-inflammatory drug hydroxychloroquine should not be used to prevent infection in people who do not have covid-19, say a WHO Guideline Development Group (GDG) panel of international experts in The BMJ today. Their strong recommendation is based on high certainty evidence from six randomised controlled trials involving over 6,000 participants with and […]

Posted inUS

The Lancet: No evidence of benefit for chloroquine and hydroxychloroquine in COVID-19 patients

May 22, 2020 – A large observational study suggests that treatment with the antimalarial drug chloroquine or its analogue hydroxychloroquine (taken with or without the antibiotics azithromycin or clarithromycin) offers no benefit for patients with COVID-19. The study analysed data from nearly 15,000 patients with COVID-19 receiving a combination of any of the four drug […]

Posted inOp-Ed

Dr. Peter G. Lurie: FDA Should Revoke Emergency Use Authorization for Hydroxychloroquine for COVID-19

May 22, 2020 – Given the lack of evidence for its effectiveness, and the new evidence that hydroxychloroquine harms patients hospitalized with COVID-19, it is time for the Food and Drug Administration to revoke its Emergency Use Authorization for the drug. It remains inexplicable why President Trump decided to politicize the prospects of hydroxychloroquine over […]

Posted inSci/Tech

New study: Hydroxychloroquine ineffective as a preventive antiviral against COVID-19

CLEVELAND, August 17, 2020 – Researchers at Case Western Reserve University have added to the growing body of understanding about how hydroxychloroquine (HCQ) is not a possible defense against COVID-19. Specifically, they found that HCQ is not effective in preventing COVID-19 in patients with lupus and rheumatoid arthritis (RA), suggesting a broader interpretation of HCQ […]

Posted inUS

Trump and public demand for unproven COVID-19 therapies

SAN DIEGO, Calif. April 29, 2020 – Since there are no FDA-approved treatments for COVID-19, people may end up searching for unproven therapies. Therefore, when several high-profile figures – including President Donald Trump and Elon Musk – endorsed the use of chloroquine and hydroxychloroquine to treat COVID-19, it brought the issue of misinformation to the […]

Posted inLife

CDC: Severe Illness Associated with Using Non-Pharmaceutical Chloroquine Phosphate to Prevent and Treat Coronavirus Disease 2019 (COVID-19)

March 28, 2020 – Chloroquine phosphate, when used without a prescription and supervision of a healthcare provider, can cause serious health consequences, including death. Clinicians and public health officials should discourage the public from misusing non-pharmaceutical chloroquine phosphate (a chemical used in home aquariums). Clinicians should advise patients and the public that chloroquine, and the […]

Posted inSci/Tech

Pharmacists warn against malarial drugs as cures for coronavirus

April 30, 2020 – Early reports that antimalarial drugs chloroquine and hydroxychloroquine could be used to prevent and cure the virus have received a caution from Huddersfield pharmacists in an article published in the British Journal of Pharmacy. PHARMACY experts at the University of Huddersfield are urging caution over claims that widely-available antimalarial drugs could […]

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Chairman Pallone Calls for Inspector General Investigation into Circumstances Surrounding Dr. Bright’s Reassignment

April 23, 2020 – “Removing Dr. Bright in the midst of a pandemic would raise serious concerns under any circumstances, but his allegations that political considerations influenced this decision heighten those concerns and demand full accountability.” Energy and Commerce Chairman Frank Pallone, Jr. (D-NJ) sent a letter to the Health and Human Services (HHS) Office of Inspector […]

Posted inSci/Tech

Researchers Identify Natural Products with Potential Efficacy Against Coronavirus, Ebola, and Other Lethal Viruses

January 5, 2021 – Researchers at Scripps Institution of Oceanography and Skaggs School of Pharmacy and Pharmaceutical Sciences at the University of California San Diego have broken down the genomic and life history traits of three classes of viruses that have caused endemic and global pandemics in the past and identify natural products – compounds […]

Posted inUS

Clyburn Issues Subpoenas To Azar And Redfield On Political Meddling In CDC’s Coronavirus Response

Washington, D.C. (December 21, 2020) — Today, Rep. James E. Clyburn, Chairman of the Select Subcommittee on the Coronavirus Crisis, issued subpoenas to Secretary of Health and Human Services (HHS) Alex M. Azar II and Director of the Centers for Disease Control and Prevention (CDC) Robert R. Redfield, ordering them to produce documents on political interference that hindered the nation’s response […]

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Lawmakers Request Communications Between FDA and White House on Potentially Politicized Convalescent Plasma Emergency Use Authorization

Washington, DC, August 25, 2020 – United States Senator Elizabeth Warren (D-Mass.), Member of the Senate Health, Education, Labor, and Pensions (HELP) Committee, and Senator Edward J. Markey are requesting copies of all communications between the Food and Drug Administration (FDA) and White House officials regarding the agency’s announcement earlier this week of an Emergency […]

Posted inSci/Tech

Study shows hydroxychloroquine’s harmful effects on heart rhythm

The malaria drug hydroxychloroquine, which has been promoted as a potential treatment for Covid-19, is known to have potentially serious effects on heart rhythms. Now, a team of researchers has used an optical mapping system to observe exactly how the drug creates serious disturbances in the electrical signals that govern heartbeat. The research, reported May […]

Posted inUS

Study: President Trump was likely the largest driver of misinformation during the COVID pandemic

October 1, 2020 – The Cornell Alliance for Science has just released a media analysis that identifies the hot topics and major players in the misinformation “infodemic” that has accompanied the global COVID-19 pandemic. The study, which evaluated 38 million articles published by English-language, traditional media worldwide, identified over 1.1 million news articles that disseminated, amplified or reported […]

Posted inUS

Documents Reveal Potential Unresolved Conflicts Of Interest Among Top Operation Warp Speed Advisors

Washington, D.C. Sept. 22, 2020 – Yesterday, Rep. James E. Clyburn, Chairman of the Select Subcommittee on the Coronavirus Crisis, sent a letter to David S. Harris, President and Chief Executive Officer of Advanced Decision Vectors (ADV), urging compliance with the Select Subcommittee’s earlier requests and releasing new documents showing significant financial conflicts of interest among top advisors of Operation […]

Posted inOp-Ed

Anita Desikan: Political Officials Undermine CDC Scientists’ COVID-19 Studies

September 15, 2020 – In a scary and dramatic shift away from normal, the entire process for publishing CDC reports on COVID-19 has been upended by political appointees at the Department of Health and Human Services (HHS) for reasons that appear to be entirely political, Politico reported late last week. Throughout the summer, including as recently as last Friday, […]

Posted inOp-Ed

Walter G. Moss: Five Strictly Professional Reasons Why Historians Dislike Donald Trump

Aug. 9, 2020 – Walter G. Moss is a professor emeritus of history at Eastern Michigan University, a Contributing Editor of HNN, and author of An Age of Progress? Clashing Twentieth-Century Global Forces (2008). For a list of his recent books and online publications click here. It is no secret that most historians dislike President Trump. In December of […]