“Although L-dopa remains the gold standard for Parkinson’s treatment, as the disease progresses, efficacy decreases, requiring higher and more frequent doses, which increases the risk of dyskinesia,” says the study’s co-corresponding author Amal Alachkar, Ph.D., associate professor of teaching in UCI’s Department of Pharmaceutical Sciences. “Our study indicates that L-dopa may play a significant role in this process.” School of Pharmacy & Pharmaceutical Sciences / UCI